As a leading supplier in the field of microarrays, Creative Proteomics is committed to designing and developing various effective biological microarray products for non-clinical research and providing corresponding testing services. Our microarray test platform provides a full range of microarray-based protein analysis and determination services for inflammatory mediators to help our global customers conduct relevant research and reduce research costs. We are confident to provide you with high-quality products and high-quality services to help scientific research.
Growth Factor Expression Analysis
Growth factors are a group of peptide-hormone-like substances that are different from any previously known hormones and have the function of stimulating the growth of cells and tissues. In animal models, the expression of many growth factors and their receptors have been reported. Growth factors are involved in cell differentiation and are essential for the normal cell cycle. In recent years, the focus of research has gradually focused on the complex signal network of growth factors in tumorigenesis and development (cell proliferation, migration) and embryonic development (cell development). From conception to death, growth factors mediate fetal development, play a role in the maintenance and repair of tissues, stimulate blood cell production and participate in the process of carcinogenesis. Abnormal production and regulation of growth factors can play a role in the progression of the disease. For example, vascular endothelial growth factor induces endothelial cells (components of capillaries) to penetrate tumor nodules and start the process of angiogenesis or capillary growth (a sign of cancer progression). The detection of the end expression of growth factors through a microarray platform has high throughput and economic benefits.
Service Process
We provide corresponding growth factor detection services based on protein microarrays and tissue microarrays. This service is mainly aimed at the quantification of downstream expression based on growth factor signal-related pathways. For the expression of growth factors at the protein level, we provide two services, including fresh samples and pathological samples.
Our growth factor protein array products can detect fresh samples from humans and laboratory animals. In organisms, growth factors can stimulate the cell division of many different cell types in target cells through endocrine, paracrine or autocrine mechanisms. Growth factors bind to receptors on the cell surface, thereby activating cell proliferation and/or differentiation. The specific instructions conveyed by growth factors to a specific subset of cells depend on the type of receptor, the number of target cells, and the intracellular signal transduction after the factor is combined.
Our tissue microarray products can be used for in situ analysis of growth factors. You can choose our products to test your target set. Or use our tissue microarray platform to form a customized tissue microarray. We will provide services for the entire process from customizing microarray products to testing, saving you time and manpower.
Fig 1. The process of protein microarray detection of growth factors.
Our Features and Benefits
- Diversified service content and application scenarios
- Strong technical platform and experienced experimental team
- One-stop service experience
Creative Proteomics provides high-quality microarray tools and convenient detection services to explore the role of growth factors. We have a large and well-equipped team of scientists who are committed to cooperating with researchers from all over the world. By choosing outsourcing testing services, your advantage is that you do not need to consider any other expenses, such as equipment, laboratory space, supervision or management. This convenient method can quickly turn around and provide reliable results, thus saving valuable time and resources. Please contact us for more detailed information.
References
- Edwards J P, Zhang X, Mosser D M. The expression of heparin-binding epidermal growth factor-like growth factor by regulatory macrophages[J]. The Journal of Immunology, 2009, 182(4): 1929-1939.
- Yang G, Zhang A, Wang J, et al. Hepatoma-derived growth factor promotes growth and metastasis of hepatocellular carcinoma cells[J]. Cell biochemistry and function, 2016, 34(4): 274-285.
For research use only, not intended for any clinical use.
