As a leading supplier in the field of microarrays, Creative Proteomics is committed to designing and developing various effective biological microarray products for non-clinical research and providing corresponding testing services. Our microarray test platform provides a full range of microarray-based protein analysis and determination services for inflammatory mediators to help our global customers conduct relevant research and reduce research costs. We are confident to provide you with high-quality products and high-quality services to help scientific research.
Inflammatory Factors Expression Profile
Inflammatory factors (inflammatory mediator proteins) include cytokines, chemokines and other small molecule proteins that are related to inflammation and are usually associated with acute and chronic disease states. As a part of cytokines, inflammatory factors are also involved in signal transduction between cells, interacting with specific cell surface receptors, leading to a signal transduction cascade that regulates inflammation and immune responses. Under physiological stress such as trauma or infection, the concentration of inflammatory mediators may increase sharply. Generally, the inflammatory mediator proteins at the site of inflammation include interleukin (IL) and cell signaling molecules, such as growth factor (GF), tumor necrosis factor (TNF), and interferon (INF), which trigger inflammation and respond to infection. In clinical studies, the expression of inflammatory factors can provide insights for distinguishing inflammatory cysts (such as pancreatic pseudocysts) and precancerous lesions.
Service Process
Our microarray service based on inflammatory factors is aimed at the expression analysis of inflammatory factors in different disease models. This service is aimed at the analysis of the expression of inflammatory mediator proteins in biological samples taken from various animal models, including the analysis of expression in fresh biological samples, as well as pathological analysis services. The analysis of this combination method is beneficial to obtain a clearer inflammation situation. You can choose to choose a single service or a combined service. Our protein microarray and tissue microarray services have experienced experimental and technical teams that can provide comprehensive services. This service is for biological samples from humans and laboratory animals. If you have other analysis needs for biological samples, you can contact our service team for customization.
Fig 1. Inflammatory factor microarray analysis service process.
Our Benefits
- Measure changes in inflammatory mediator proteins in specific animal models or disease samples
- Discover potential candidate biomarkers
- Compare the profiles of normal, model and treated samples
Creative Proteomics provides high-quality microarray tools and convenient detection services for studying the inflammatory protein profile of inflammation-related signals. We have a large and well-equipped team of scientists who are committed to cooperating with researchers from all over the world. By choosing outsourcing testing services, your advantage is that you do not need to consider any other expenses, such as equipment, laboratory space, supervision or management. This convenient method can quickly turn around and provide reliable results, thus saving valuable time and resources. Please contact us for more detailed information.
References
- Puig-Costa M, Codina-Cazador A, Cortés-Pastoret E, et al. Discovery and validation of an INflammatory PROtein-driven GAstric cancer Signature (INPROGAS) using antibody microarray-based oncoproteomics[J]. Oncotarget, 2014, 5(7): 1942.
- Lee L S, Banks P A, Bellizzi A M, et al. Inflammatory protein profiling of pancreatic cyst fluid using EUS-FNA in tandem with cytokine microarray differentiates between branch duct IPMN and inflammatory cysts[J]. Journal of immunological methods, 2012, 382(1-2): 142-149.
- Dionne K, Redfern R L, Nichols J J, et al. Analysis of tear inflammatory mediators: A comparison between the microarray and Luminex methods[J]. Molecular vision, 2016, 22: 177.
For research use only, not intended for any clinical use.
